Sherif NA, El-Banna AS, ElBourini MM, Khalil NO. 2010;32(9):1109-1114. I take alpha lipoic acid and acetyl L carnitine twice a day, everyday. View abstract. Cureus. View abstract. Waldner, R., Laschan, C., Lohninger, A., Gessner, M., Tuchler, H., Huemer, M., Spiegel, W., and Karlic, H. Effects of doxorubicin-containing chemotherapy and a combination with L-carnitine on oxidative metabolism in patients with non-Hodgkin lymphoma. According to the University of Maryland Medical Center, carnitine is successful in treating hyperthyroidism possibly because of its ability to block the effects of thyroid hormones - a potentially dangerous effect for people suffering from an underactive thyroid. Scarpini E, Sacilotto G, Baron P, et al. Efficacy of L-propionylcarnitine treatment in patients with left ventricular dysfunction. View abstract. As stated previously, foods high in sugar and saturated fat have been associated with poor sleep quality and sleep disturbances . Wang, Y. X., Yang, S. W., Qu, C. B., Huo, H. X., Li, W., Li, J. D., Chang, X. L., and Cai, G. Z. View abstract. View abstract. Nephrol.Dial.Transplant. View abstract. Chinese J.Pract.Internal Med. Am.J Cardiol. Alternative medical interventions used in the treatment and management of myalgic encephalomyelitis/chronic fatigue syndrome and fibromyalgia. Pediatr.Nephrol. View abstract. View abstract. Weinhandl, E. D., Rao, M., Gilbertson, D. T., Collins, A. J., and Pereira, B. J. J Inherit.Metab Dis 2008;31(3):361-367. Effects of L-propionylcarnitine on ischemia-induced myocardial dysfunction in men with angina pectoris. Optom.Vis.Sci 2011;88(12):1439-1444. (Paris) 2010;166(3):289-294. 2006;142(4):458-460. Levocarnitine for asparaginase-induced hepatic injury: a multi-institutional case series and review of the literature. As a supplement, acetyl-L-carnitine is usually considered safe when taken as directed. Many studies show that eating eggs regularly can improve health. Cipolli, C. and Chiari, G. [Effects of L-acetylcarnitine on mental deterioration in the aged: initial results]. Additional anti-ischemic effects of long-term L-propionylcarnitine in anginal patients treated with conventional antianginal therapy. View abstract. Med.Sci Monit. Prevention of hepatotoxicity recurrence with valproate monotherapy and carnitine. Baghban F, Hosseinzadeh M, Mozaffari-Khosravi H, Dehghan A, Fallahzadeh H. The effect of L-Carnitine supplementation on clinical symptoms, C-reactive protein and malondialdehyde in obese women with knee osteoarthritis: a double blind randomized controlled trial. J Strength.Cond.Res. Efficacy and safety of adefovir dipivoxil with antiretroviral therapy. 2011;18(1):18-22. Acta Neurol.Scand. Dutta, A., Ray, K., Singh, V. K., Vats, P., Singh, S. N., and Singh, S. B. L-carnitine supplementation attenuates intermittent hypoxia-induced oxidative stress and delays muscle fatigue in rats. View abstract. Dimitriadis, F., Tsambalas, S., Tsounapi, P., Kawamura, H., Vlachopoulou, E., Haliasos, N., Gratsias, S., Watanabe, T., Saito, M., Miyagawa, I., and Sofikitis, N. Effects of phosphodiesterase-5 inhibitors on Leydig cell secretory function in oligoasthenospermic infertile men: a randomized trial. Since L-carnitine helps move more fatty acids into your cells to be burned for energy, you might think this would increase your ability to burn fat and lose weight. Immunopharmacol.Immunotoxicol. View abstract. J Int.Soc.Sports Nutr. Hiraoka A, Kiguchi D, Ninomiya T, et al. Koeth RA, Wang Z, Levison BS, Buffa JA, Org E, Sheehy BT, Britt EB, Fu X, Wu Y, Li L, Smith JD, DiDonato JA, Chen J, Li H, Wu GD, Lewis JD, Warrier M, Brown JM, Krauss RM, Tang WH, Bushman FD, Lusis AJ, Hazen SL. L-Carnosine Dosage. 2010;21(7):580-588. View abstract. In theory, using L-carnitine as a weight loss supplement makes sense. View abstract. Acta Anaesthesiol.Scand. Nausea and vomiting Diarrhea Other possible side effects may include: Headaches and dizziness Insomnia Fatigue Skin itching or rashes Irritability or agitation The safety of use of CoQ10 during pregnancy and breast-feeding hasn't been established. Patients with medium-chain acyl-coenzyme a dehydrogenase deficiency have impaired oxidation of fat during exercise but no effect of L-carnitine supplementation. View abstract. View abstract. 2007;20(5):499-502. J Nephrol. The equivalent dosage range for other forms of L-carnitine are as follows: 630-2,500mg (ALCAR), 1,000-4,000mg . Asbaghi O, Kashkooli S, Amini MR, et al. Ismail AM, Hamed AH, Saso S, Thabet HH. J Autism Dev.Disord. Miyagawa T, Kawamura H, Obuchi M, Ikesaki A, Ozaki A, Tokunaga K, Inoue Y, Honda M. Effects of oral L-carnitine administration in narcolepsy patients: a randomized, double-blind, cross-over and placebo-controlled trial. View abstract. The effect of (L-)carnitine on weight loss in adults: a systematic review and meta-analysis of randomized controlled trials. Lisinopril (lisinipril) should be stopped if there are symptoms or signs of an allergic reaction including feelings of swelling of the face, lips, tongue or throat. Do not take extra medicine to make up the missed dose. The effect of preoperative L-carnitine supplementation on myocardial metabolism during aorto-coronary-bypass surgery. Eur Heart J 1996;17:414-20. Wang Y, Xu Y, Zou R, et al. By naturally getting rid of brain fog while assisting with problematic insomnia issues, N-Acetyl-L-Carnitine is the optimal inclusion in the ProMind Complex formula that will also enhance energy . Last updated on Aug 31, 2022. View abstract. Cardiologia 1989;34(7):651-655. J Inherit.Metab Dis 2008;31 Suppl 2:S219-S222. J Pharm Sci 1995;84(5):627-633. Malaguarnera, M., Risino, C., Cammalleri, L., Malaguarnera, L., Astuto, M., Vecchio, I., and Rampello, L. Branched chain amino acids supplemented with L-acetylcarnitine versus BCAA treatment in hepatic coma: a randomized and controlled double blind study. View abstract. Additionally, the risk of deficiency is higher for those with diseases like cirrhosis and kidney disease. View abstract. Medically reviewed by Drugs.com. Gynecol Endocrinol 2019;35(8):701-5. doi: 10.1080/09513590.2019.1576622. Cardiovasc Drugs Ther 1990;4:481-6. View abstract. These 11 healthy foods can help you burn fat. As a supplement, acetyl-L-carnitine is usually considered safe when taken as directed. Abdollahi H, Abdolahi M, Sedighiyan M, Jafarieh A. Laforet, P. and Vianey-Saban, C. Disorders of muscle lipid metabolism: diagnostic and therapeutic challenges. Kitano Y, Hashimoto S, Matsumoto H, et al. Guan, Y., Zheng, X. M., Yang, Z. W., and Li, S. W. [Protective effects of L-carnitine upon testicular ischemia-reperfusion damage in rats]. Lund, A. M., Joensen, F., Hougaard, D. M., Jensen, L. K., Christensen, E., Christensen, M., Norgaard-Petersen, B., Schwartz, M., and Skovby, F. Carnitine transporter and holocarboxylase synthetase deficiencies in The Faroe Islands. Tabibi, H., Hakeshzadeh, F., Hedayati, M., and Malakoutian, T. Effects of l-carnitine supplement on serum amyloid A and vascular inflammation markers in hemodialysis patients: a randomized controlled trial. View abstract. Acta Chir Scand Suppl 1983;517:157-164. Martinotti, G., Reina, D., Di, Nicola M., Andreoli, S., Tedeschi, D., Ortolani, I., Pozzi, G., Iannoni, E., D'Iddio, S., and Janiri, L. Acetyl-L-carnitine for alcohol craving and relapse prevention in anhedonic alcoholics: a randomized, double-blind, placebo-controlled pilot trial. View abstract. Long-term acetyl-L-carnitine treatment in Alzheimer's Disease. Low levels of L-carnitine have been found to be associated with diabetic complications. View abstract. Sandor, A., Pecsuvac, K., Kerner, J., and Alkonyi, I. Chao, H. H., Chen, C. H., Liu, J. C., Lin, J. W., Wong, K. L., and Cheng, T. H. L-Carnitine attenuates angiotensin II-induced proliferation of cardiac fibroblasts: role of NADPH oxidase inhibition and decreased sphingosine-1-phosphate generation. View abstract. WebMD does not provide medical advice, diagnosis or treatment. View abstract. Be sure to have your blood checked regularly. J Pediatrics 1991;118:646-9. View abstract. It is unlikely to cause significant weight loss. Suchitra, M. M., Ashalatha, V. L., Sailaja, E., Rao, A. M., Reddy, V. S., Bitla, A. R., Sivakumar, V., and Rao, P. V. The effect of L-carnitine supplementation on lipid parameters, inflammatory and nutritional markers in maintenance hemodialysis patients. Clin Ther 2010;32(4):710-713. View abstract. J.Nutr.Health Aging 2010;14(3):224-230. This study therefore aimed to examine the effect of l-carnitine supplementation on body weight and composition by including the maximum number of randomized controlled trials (RCTs) and to conduct a dose-response analysis, for the first . Yarizadh H, Shab-Bidar S, Zamani B, Vanani AN, Baharlooi H, Djafarian K. The effect of L-carnitine supplementation on exercise-induced muscle damage: A systematic review and meta-analysis of randomized clinical trials. View abstract. Enhancement of activities relative to fatty acid oxidation in the liver of rats depleted of L-carnitine by D-carnitine and a gamma- butyrobetaine hydroxylase inhibitor. View abstract. View abstract. Famularo, G., Moretti, S., Alesse, E., Trinchieri, V., Angelucci, A., Santini, G., Cifone, G., and De, Simone C. Reduction of glutamate levels in HIV-infected subjects treated with acetylcarnitine. View abstract. L-Carnitine is used to treat carnitine deficiency. Urol.J 2010;7(3):188-193. View abstract. Nasca D, Zurria G, and Aguglia E. Action of acetyl-L-carnitine in association with mianserine on depressed old people. Jacobs, P. L., Goldstein, E. R., Blackburn, W., Orem, I., and Hughes, J. J. Glycine propionyl-L-carnitine produces enhanced anaerobic work capacity with reduced lactate accumulation in resistance trained males. Melegh, B., Kerner, J., Sandor, A., Vinceller, M., and Kispal, G. Effects of oral L-carnitine supplementation in low-birth-weight premature infants maintained on human milk. View abstract. Rodriguez DR, endible A, Gomez N, and et al. 2009;4(27):45-52. View abstract. View abstract. Am J Cardiol 1994;74:125-30. Am.J Clin Oncol. Carnitine and physical exercise. Karanth, J. and Jeevaratnam, K. Effect of dietary lipid, carnitine and exercise on lipid profile in rat blood, liver and muscle. Rossini, P. M., Marchionno, L., Gambi, D., Pirchio, M., Del Rosso, G., and Albertazzi, A. EMG changes in chronically dialyzed uraemic subjects undergoing d, 1- Carnitine treatment. JPEN J Parenter.Enteral Nutr 1988;12(6):555-562. The effect of carnitine in patients using artificial pacemakers. This may lead to irritability, hyperactivity or insomnia. Tumori 2005;91(2):135-138. A., and Farok, M. Assessment of puberty in relation to L-carnitine and hormonal replacement therapy in beta-thalassemic patients. Int.J Sport Nutr.Exerc.Metab 2011;21(5):385-397. Effects of L-carnitine on leukocyte function and viability in hemodialysis patients: A double-blind randomized trial. View abstract. L-Carnosine (-alanyl-L-histidine) is a dipeptide of the amino acids beta-alanine and histidine. View abstract. View abstract. Blood 1998;91:3817-24. Mettang, T., Thomas, S., and Kuhlmann, U. L-carnitine does not alleviate uremic pruritus in hemodialysis patients. Scaglia F, Longo N. Primary and secondary alterations of neonatal carnitine metabolism. 10-21-2011;17(39):4414-4420. Abbasnezhad A, Hasanavand A, Falahi E, Kashkooli S, Asbaghi O, Choghakhori R. Effect of L-carnitine supplementation on lipid profiles of patients with liver disease: a systematic review and meta-analysis. 1991;13(1-2):135-146. Zhang, Y., Song, J. Q., Liu, P., Yan, R., Dong, J. H., Yang, Y. L., Wang, L. F., Jiang, Y. W., Zhang, Y. H., Qin, J., and Wu, X. R. [Clinical studies on fifty-seven Chinese patients with combined methylmalonic aciduria and homocysteinemia]. If you do not have a dose-measuring device, ask your pharmacist for one. 2007;71(Pt 6):705-712. Tarantini, G., Scrutinio, D., Bruzzi, P., Boni, L., Rizzon, P., and Iliceto, S. Metabolic treatment with L-carnitine in acute anterior ST segment elevation myocardial infarction. Seattle, WA: University of Washington, Seattle;1993. Pietropaoli, P., Caporelli, S., De Pace, F., Donati, A., Adrario, E., Luzi, A., Munch, C., Giovannini, C., and Frezzotti, A. R. [Intraoperative lactic acidosis, can it be treated? View abstract. View abstract. View abstract. Evaluation of the effects of L-acetylcarnitine on senile patients suffering from depression. Karl M, Rubenstein M, Rudnick C, Brejda J. View abstract. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. J Strength.Cond.Res. Am J Mens Health 2021;15(5):15579883211036790. . Reversal of haemodialysis induced hypertriacylglycerolemia by L-carnitine. View abstract. Electromyogr.Clin Neurophysiol. In an eight-week study in 38 women who exercised four times per week, there was no difference in weight loss between those who took L-carnitine and those who didnt (24). View abstract. 2010;105(6):1338-1345. Prostaglandins Leukot.Essent.Fatty Acids 2002;67(1):33-38. A., Thelen, J. The effect of levocarnitine for plasmatic matrix metalloproteinases (MMPS) on acute cerebral infarct patients. View abstract. Liu J, Head E, Kuratsune H, et al. View abstract. Cherchi A, Lai C, Angelino F, et al. NAC is an amino acid, something present in many foods, but supplements give you a higher dose than you'd get in your daily diet. Moustafa, A. M. and Boshra, V. The possible role of L-carnitine on the skeletal muscle of ovariectomized rats. View abstract. Roure, R., Oddos, T., Rossi, A., Vial, F., and Bertin, C. Evaluation of the efficacy of a topical cosmetic slimming product combining tetrahydroxypropyl ethylenediamine, caffeine, carnitine, forskolin and retinol, In vitro, ex vivo and in vivo studies. A., Kraemer, W. J., Hatfield, D. L., Vingren, J. L., Fragala, M. S., Ho, J. Y., Thomas, G. A., Hakkinen, K., and Volek, J. S. Effects of L-carnitine L-tartrate supplementation on muscle oxygenation responses to resistance exercise. Pucciarelli, G., Mastursi, M., Latte, S., Sacra, C., Setaro, A., Lizzadro, A., and Nolfe, G. [The clinical and hemodynamic effects of propionyl-L-carnitine in the treatment of congestive heart failure]. 2007;29(8):517-530. Duranay, M., Akay, H., Yilmaz, F. M., Senes, M., Tekeli, N., and Yucel, D. Effects of L-carnitine infusions on inflammatory and nutritional markers in haemodialysis patients. Most people tolerate L-carnitine well. "The first study found that people who ate a lot of red meat had a certain type of bacteria in their system that broke the compound down into TMAO and raised their risk for heart disease," he explained. View abstract. Role of acetyl-L-carnitine in the treatment of cognitive deficit in chronic alcoholism. Drugs Exptl Clin Res 1992;18(1):29-36. 2006;16(4):281-287. Some dosage forms listed on this page may not apply to the brand name L-Carnitine. Semin Perinatol 1999;23:152-61. Jpn Heart J 1995;36(3):319-331. View abstract. View abstract. 1. View abstract. View abstract. Medicine (Baltimore). 2005-2023 Healthline Media a Red Ventures Company. The liquid medicine can be taken alone or mixed with a beverage or soft food. Moncada ML, Vicari E, Cimino C, et al. Abbasnezhad A, Choghakhori R, Kashkooli S, Alipour M, Asbaghi O, Mohammadi R. Effect of L-carnitine on liver enzymes and biochemical factors in hepatic encephalopathy: A systematic review and meta-analysis. Reprod.Biomed.Online. (Rome) 2010;11(9):703-705. This thread is archived The effects of L-carnitine supplementation on performance during interval swimming. It plays a crucial role in the production of energy by transporting fatty acids into your cells mitochondria (1, 2, 3). L-carnitine may aid weight loss. Oral carnitine supplementation reduces body weight and insulin resistance in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. Side effects may include nausea, gastrointestinal discomfort, bloating, diarrhea, hives, lower back pain, leg restlessness, numbness, rash, endocrine changes, increased inflammatory response, increased blood urea nitrogen, severe tissue necrosis and venous irritation. View abstract. View abstract. Protective role of carnitine in breast cancer via decreasing arginase activity and increasing nitric oxide. Available for Android and iOS devices. The therapeutic effect of L-carnitine in patients with exercise-induced stable angina: a controlled study. View abstract. (Pakistan) 2006;6(5):800-805. Tell your doctor if you are pregnant or plan to become pregnant. Cacciatore L, Cerio R, Ciarimboli M, et al. Hypertension 2009;54(3):567-574. Immunopharmacol.Immunotoxicol. Med.Sci Monit. Long-Term Levocarnitine Ameliorates Left Ventricular Diastolic as Well as Systolic Dysfunction in Hemodialysis Patients - Multi-Center Study. Sato S, Namisaki T, Furukawa M, et al. Dial Transplant 1998;27:498-506. View abstract. First, take your CoQ10 with a meal. 1996;208(3):129-134. Indian J Exp.Biol. Myocardial response to pretreatment with L-carnitine in patients with cardiac valve replacement. Int J Clin Pharmacol Res 1990;10:75-9. Clin Drug Invest 1996;11(2):90-96. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Toptas, B., Baykal, A., Yesilipek, A., Isbir, M., Kupesiz, A., Yalcin, O., and Baskurt, O. K. L-carnitine deficiency and red blood cell mechanical impairment in beta-thalassemia major. Br J Cancer 2002;86:1854-7. Int Psychoger 1998;10:193-203. View abstract. Hart AM, Wilson AD, Montovani C, et al. View abstract. Exp.Clin Endocrinol.Diabetes 2010;118(10):735-740. Csiky, B., Nyul, Z., Toth, G., Wittmann, I., Melegh, B., Rauh, M., Rascher, W., and Sulyok, E. L-carnitine supplementation and adipokines in patients with end-stage renal disease on regular hemodialysis. View abstract. Antioxidant treatment with carnitines is effective in infertile patients with prostatovesiculoepididymitis and elevated seminal leukocyte concentrations after treatment with nonsteroidal anti-inflammatory compounds. Srivastava DK, Kumar S Misra AP. Comparison of pharmacokinetics of L-carnitine, acetyl-L-carnitine and propionyl-L-carnitine after single oral administration of L-carnitine in healthy volunteers. View abstract. Sawicka AK, Hartmane D, Lipinska P, Wojtowicz E, Lysiak-Szydlowska W, Olek RA. Oncologist. Borghi-Silva, A., Baldissera, V., Sampaio, L. M., Pires-DiLorenzo, V. A., Jamami, M., Demonte, A., Marchini, J. S., and Costa, D. L-carnitine as an ergogenic aid for patients with chronic obstructive pulmonary disease submitted to whole-body and respiratory muscle training programs.